About the RoleWe are seeking a postdoctoral research assistant to join the group of Dr Mirjana Efremova in the Centre for Cancer Evolution, to work on a CRUK funded project to investigate the role of inflammation on therapy resistance in colorectal cancer. Our lab is focused on understanding the cellular and molecular mechanisms promoting metastasis and therapy resistance in colorectal cancer. We use single-cell multiomics and spatial transcriptomics data from patient samples and patient-derived organoids (Ogden et al., Cell Genomics 2025, Efremova et al. Nature; Efremova et al., Cell Reports) and develop computational methods (Efremova et al. Nature Protocols, 2020; Jain et al., Genome Biology).About YouPhD in a biological or computational subject and background in working with genomics data.About the School/Department/Institute/ProjectThe Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre (together with UCL, Kings and the Francis Crick Institute) which i